Atletico Madrid vs. Manchester United time, TV channel, stream, lineups, betting odds for UEFA Champions League Round of 16

Manchester United travel to face Atletico Madrid in Wednesday’s UEFA Champions League Round of 16 first-leg clash fresh off the back of a 4-2 Premier League win over rivals Leeds United at the weekend.

Next up, Man United face Atleti in Europe for the first time in over three decades.

It could be a good time to renew acquaintances. Diego Simeone’s men have not been in the best of form, losing three out of their last four matches. However, the Colchoneros did pick up a win in their most recent encounter, and it was a convincing one, too — a 3-0 away victory over Osasuna.

Manchester United earned the right to host the second leg at Old Trafford after finishing in first place in their Champions League group. Atletico Madrid came in second place behind Liverpool in their group.

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How to watch Atletico Madrid vs. Man United in the USA

• Date: Wednesday, Feb. 23
• Time: 3 p.m. ET (8 p.m. GMT)
• TV Channels: CBS, Univision, TUDN
• Streaming: fuboTV, Paramount+

For U.S. viewers, the match will air on CBS (English) and on Univision and TUDN (Spanish) with all three channels streamed on fuboTV, which is available to new users on a free trial.

The match will also be streamed on CBS streaming Paramount+ for subscribers.

MORE: Complete Round of 16 Champions League schedule & results

Atletico Madrid vs. Manchester United predicted lineups

Antoine Griezmann and Luis Suarez are expected to start on the bench, with Joao Felix and Angel Correa leading the Atleti attack. 

Koke, Matheus Cunha and Daniel Wass are out through injury, while Yannick Carrasco is suspended.

Atletico Madrid projected lineup: Oblak — Vrsaljko, Savic, Gimenez, Reinildo, Lemar — Llorente, Kondogbia, Herrera — Correa, Felix.

Eric Bailly has returned to training after recovering from an ankle injury. Phil Jones has been added to the Champions League squad and is eligible for selection. Raphael Varane played the final minutes of Sunday’s match against Leeds after recovering from illness.

The question manager Ralf Rangnick will have is which forward trio to line up: Only two of Anthony Elanga, Marcus Rashford and Jadon Sancho will take the field either side of Cristiano Ronaldo.

Manchester United projected lineup: De Gea — Wan-Bissaka, Varane, Maguire, Shaw — McTominay, Pogba, Fernandes — Elanga, Sancho, Ronaldo.

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Atletico Madrid vs. Man United betting odds and picks

Odds courtesy of DraftKings

Expect goals at the Wanda Metropolitano as United face Atleti.

Rangnick’s men might be the very definition of inconsistent so far this campaign. However, it’s not been the best of seasons for the Spanish champions either. They currently sit fifth in La Liga, 15 points behind leaders Real Madrid.

Simeone’s team isn’t as impenetrable as it once was — Atleti score plenty, but also leak a few. Even though they beat Osasuna at the weekend, they only managed 38 percent possession.

United to get the first goal (+115) looks a good pick, as does Cristiano Ronaldo to score any time (+210) given how much he has enjoyed playing against the Colchoneros throughout his career.

• Moneyline: Atletico Madrid +175 / Draw +215 / Man United +180
• Spread: Atletico Madrid -0.5 (+175) / Man United +0.5 (-200)
• O/U 2.5 goals: Over +115 / Under -145 
• Both teams to score: Yes -120 / No -105